Teenagers hear their mother's confession of incest, sexual blackmail and seduction, at the last reunion they will ever know. They gain new understanding of their family's past and what it means to be human.
Take one lightly-populated overnight express bus, add one alien-controlled human being and a mysterious substance disguised as anti-bacterial soap, stir well, and you've got an orgy, a transformation, and a possible suicide, all-in-one!
Lois has herself sent to her boyfriend wrapped up as his birthday present. She pops out of the box to find she's been delivered to the wrong address, much to the delight of 4 black men.