This story takes place in that short gap between 'The Andy Griffith Show' original series and the 'Mayberry RFD' series. right before the wedding episode.
Vault 76 has 'Programs' that everyone is issued and must follow for the good of the vault. Many of these 'Programs' are sexual in nature, but residents opt into them willingly. Samantha opts in, wanting to be an asset to the vault. This leads her down a path she never imagined, taking every wrong turn possible. Some points in this story jump between scenes rapidly, hopefully they aren't too bad to follow along with :)