'Lifers' and reprobates of various kinds are sent to a remote Pacific penal colony when they have embarrassed their government too many times by escaping other prisons etc. No death penalty existing. The island is made up of two halves; little or nothing is known about the other half, and as there is very little supervision in what is basically an open prison, meaning many prisoners simply depart at will for the unknown; the female Governor turns a blind eye to this: aware they won't return.
Women are drugged and kidnapped to become 'sexual-toys' for other men and women. After their 'use', the girls are subjected as 'test-animals' for various new drugs that are being tested, which all the drugs seem to lead to their untimely death.