Chapter 2: Susan and the Discovery of tx34

After the thrusts with Tania while she was in the MRI scanner, the curiosity in me (I am a researcher, after all) made me look carefully at the brain scans during our fuck. After our first fuck in her fertile phase, this task distracted me from worrying about impregnating her.

It was fascinating to see which areas of her brain were activated during orgasm. Because our machine had the unique ability to observe neural activity with microsecond time resolution, I was able to pinpoint the neural network at the onset of the orgasmic surge. I found a mysterious network of neurons spread throughout most of her brain in thin filaments - very unusual and previously unreported.

I called this network the ‘horny web’ because of its effect on Tania. Now that I knew what to look for, I found this enigmatic network in all of the female brain scans - but never in any of the male brain scans we had for comparison.

Tania’s ‘horny web’ was much more developed than in the other women, which made it possible to find it. If you knew where to look, you could find it in other women. It was a lucky coincidence that I came across this unusually ‘slutty’ girl with her comparatively thick ‘horny web’ and happened to observe it activated!

Adding to the mystery, Tania’s ‘horny web’ was far more activated than any of the other subjects, even before I had touched her. Could this have something to do with her initial horny mood?

She had given me the opportunity to compare her ‘horny web’ activation at two stages of her menstrual cycle with her second visit to my lab. It became glaringly obvious that only during ovulation was the ‘horny web’ fully pre-activated.

Over the next few weeks, I refined my analysis to the point where I could say with confidence: Tania’s initial arousal, her lack of inhibition about having sex with a stranger, was related to the exceptionally strong activity in the mysterious female ‘horny web’ network.

My second phase of research focused on identifying the types of neurons within this network. To my great surprise, I found that this network was made up of an obscure type of nerve cell that scientists had largely overlooked simply because of its low abundance.

Male brains had virtually none of this type of neuron. There was a small exception in a region of the brain associated with judgment, self-control, and restraint. But they were all over the female brain in microscopic filaments that had apparently escaped notice.

I searched the literature on these exotic neurons, which I called ‘horny neurons’, and found only one publication that reported the gene expression profile of these cells. The gene expression profile is specific to each cell type and describes which of the approximately 21,000 known human genes were ‘used’ in that particular cell (‘used’ refers to the gene being transcribed from DNA and then translated into proteins, which are the building blocks of cells).

By comparing the gene expression profile with other cell types, I tried to identify genes that were uniquely expressed in the horny neurons. Eventually, I narrowed it down to a single gene that appeared to encode a cellular receptor. Interestingly, virtually no one seemed to have done any work on this receptor.

Structurally, the receptor, which I named the ‘horny receptor’, was similar to receptors for other female hormones involved in the menstrual cycle. Since I was an expert on these hormones and their receptors, given the topic of my Ph.D., I recognized the telltale characteristics of an ovulation-specific receptor.

As a trained biochemist, I had no difficulty validating this hypothesis by genetically expressing the ‘horny’ receptor in a lab-grown human cell line. When I added a small amount of blood from an ovulating subject, the cells in my petri dish gave a strong sign of membrane depolarization - the kind of thing that triggers neuronal activation. Blood from other phases of the menstrual cycle did not produce this response.

If activation of this receptor had turned Tania into the horny vixen who had come to my lab with the clear intention of seducing me, then there was obviously an intriguing use for a drug that stimulated it. The thought of what could be done with such a drug made my dick hard and caused me to play the recording of my session with Tania over and over again as I masturbated.

I had no idea what to do next until one day I ran into an old friend.

Over lunch, he shared with me his progress on a predictive code that he claimed had the potential to revolutionize the field of drug development. He described a fusion of cutting-edge AI models that used the three-dimensional structures of arbitrary proteins, predicted only from their genetic sequences, to design small molecules that would bind to those proteins with orders of magnitude higher affinity than their natural substrates. Natural substrates can include hormones, neurotransmitters, or intracellular signals.

The promise was that these small molecules could effortlessly alter cellular function. The most startling claim was that the code could design these small molecules - essentially drugs - to avoid binding to other human proteins, effectively eliminating potential side effects. If successful, this breakthrough code could cut the drug development timeline from the typical 12 years to as little as 12 days.

Impressed by his claims, I couldn’t resist asking my friend to test his approach on the particular receptor I was interested in, though I kept its specific function to myself. A few weeks later, he slipped a piece of paper with a chemical structure across my desk.

To avoid further questions, I casually mentioned that my focus had shifted to several different receptors. I went on to write down a list of those that had been the subject of my real Ph.D. work. He seemed annoyed, muttered something about not running a drug design service, and quickly moved on.

After he left, I examined the potential drug he had provided. Not being a synthetic chemist, the intricacies of its chemical structure were lost on me. Fortunately, one of my roommates happened to be a talented organic chemist. Later that day, I casually asked his opinion about the substance and how to obtain it.